Study of the effectiveness of pharmaceutical intervention in improving therapeutic adherence in patients with asthma and COPD
DOI:
https://doi.org/10.60103/phc.v27.e881Keywords:
asthma; COPD; therapeutic adherence; community pharmacist; inhalerAbstract
Introduction: Drugs administered by inhalation are recommended for the treatment of respiratory diseases, but they present difficulties in their management and therapeutic adherence with these drugs is less than 50%, which leads us to study the effectiveness of the intervention of the community pharmacist to improve the process of using these devices, increase therapeutic adherence and control of these pathologies.
Method: A non-controlled, non-randomized prospective study. The Therapeutic Adherence Service assessed adherence with the Morisky-Green test, asthma control with the ACT questionnaire, and the measurement of Peak Expiratory Flow (PEF), COPD control with the CAT questionnaire, and perceived quality of life with the Visual Analog Scale (VAS), in two visits.
Results: Of the total patients included in the study (n=80), 62.5% had asthma and 37.5% had COPD. Among asthma patients, adherence increased from 30.0% to 68.0% with a 1.9-point improvement (SD: 3.2) in the ACT test, and 80.0% either improved or maintained their quality of life. Among COPD patients, adherence increased from 16.7% to 53.3%, with a -2.4-point improvement (SD: 6.0) in the CAT test, and 83.3% either improved or maintained their quality of life.
Conclusions: The provision of the Therapeutic Adherence Service increased the number of adherent patients by 35.0% and showed a positive impact on the clinical control of both conditions and on quality of life.
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References
Lestón M. Uso correcto de los dispositivos de inhalación en asma y EPOC. Butlletí de Prevenció d’Errors de Medicació de Catalunya [Internet]. 2022;20(2). Disponible en: https://scientiasalut.gencat.cat/bitstream/handle/11351/8191/butll_prev_errors_medicacio_cat%20alunya_2022_20_02_ca.pdf?sequence=1&isAllowed=y
Gaztelurrutia L. Seguimiento del asma desde la farmacia comunitaria. Argibideak [Internet]. 2022;32(4). Disponible en: https://www.cofbizkaia.eus/download/argibideak-2022-volumen-32-numero-4/
Gaztelurrutia L. EPOC: seguimiento y cribado desde la farmacia, ¿qué se puede hacer? Argibideak [Internet]. 2022;32(2). Disponible en: https://www.cofbizkaia.eus/download/argibideak-2022-volumen-32-numero-2/
GEMA 5.3. Guía Española para el manejo del Asma [Internet]. [Acceso fecha] Disponible en: https://www.gemasma.com/
Armour CL, Reddel HK, Lemay KS, Saini B, Smith LD, Bosnic-Anticevich SZ, et al. Feasibility and effectiveness of an evidence-based asthma service in Australian community pharmacies: a pragmatic cluster randomized trial. J Asthma. 2013;50:302-9. Disponible en: https://www.tandfonline.com/doi/abs/10.3109/02770903.2012.754463?journalCode=ijas20
Fathima M, Naik-Panvelkar P, Saini B, Armour CL. The role of community pharmacists in screening and subsequent management of chronic respiratory diseases: a systematic review. Pharmacy Pract (Granada) [Internet]. 2013;11(4):228-45. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1885-642X2013000400008&lng=es&tlng=en
Basheti IA, Reddel HK, Armour CL, Bosnic-Anticevich SZ. Improved asthma outcomes with a simple inhaler technique intervention by community pharmacists. J Allergy Clin Immunol. 2007;119:1537-8. Disponible en: https://www.jacionline.org/article/S0091-6749(07)00439-3/fulltext
Giraud V, Allaert FA, Roche N. Inhaler technique and asthma: feasibility and acceptability of training by pharmacists. Respir Med. 2011;105:1815-22. Disponible en: https://www.sciencedirect.com/science/article/pii/S0954611111002186
Mubarak N, Hatah EM, Khan TM, Zin CS. A systematic review and meta-analysis of the impact of collaborative practice between community pharmacist and general practitioner on asthma management. J Asthma Allergy. 2019;12:109-53. Disponible en: https://www.dovepress.com/a-systematic-review-and-meta-analysis-of-the-impact-of-collaborative-p-peer-reviewed-fulltext-article-JAA
Giraud V, Allaert FA, Roche N. Inhaler technique and asthma: feasibility and acceptability of training by pharmacists. Respir Med. 2011;105(12):1815-22. Disponible en: https://pubmed.ncbi.nlm.nih.gov/21802271/
García V, Gastelurrutia MA, Malet A, Peiró T, Pérez B, Saez L, et al. Diseño, evaluación del impacto e implantación de un servicio profesional de adherencia terapéutica desde el ámbito de la farmacia comunitaria. Proyecto AdherenciaMED. Consejo General de Colegios Oficiales de Farmacéuticos [Internet]. 2019. Disponible en: https://www.farmaceuticos.com/farmaceuticos/farmacia/farmacia-asistencial/proyectos-de-investigacion/proyecto-adherenciamed/
Global Initiative for Chronic Obstructive Lung Disease. 2023 Report [Internet]. Disponible en: https://goldcopd.org/2023-gold-report-2/
Foro de Atención Farmacéutica-Farmacia Comunitaria (Foro AF-FC), panel de expertos. Guía práctica para los Servicios Profesionales Farmacéuticos Asistenciales desde la Farmacia Comunitaria. Madrid: Consejo General de Colegios Oficiales de Farmacéuticos; 2024. Disponible en: https://www.farmaceuticos.com/wp-content/uploads/2024/02/GUIA_SPFA_FORO_2024_V15_AC-digital.pdf
Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24:67–74. Disponible en: https://journals.lww.com/lww-medicalcare/abstract/1986/01000/concurrent_and_predictive_validity_of_a.7.aspx
Vega JM, Badia X, Badiola C, Lopez-Vina A, Olaguibel JM, Picado C, et al. Validation of the Spanish version of the Asthma Control Test (ACT). J Asthma. 2007;44(10):867-72. Disponible en: https://www.tandfonline.com/doi/full/10.1080/02770900701752615
Stallberg B, Nokela M, Ehrs PO, Hjemdal P, Jonsson EW. Validation of the clinical COPD Questionnaire (CCQ) in primary care. Health Qual Life Outcomes. 2009;7:26. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC2666647/
Carpenter JC. A meta-analysis of the effectiveness of health belief model variables in predicting behavior. Health Communication. 2010;25(8):661–669. Disponible en: https://www.researchgate.net/publication/49679591_A_Meta-Analysis_of_the_Effectiveness_of_Health_Belief_Model_Variables_in_Predicting_Behavior
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